Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells

  title={Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells},
  author={Jyoti Nautiyal and Shailender Singh Kanwar and Yingjie Yu and Adhip P. N. Majumdar},
  booktitle={Journal of molecular signaling},
Metastatic colorectal cancer remains a serious health concern with poor patient survival. Although 5-Fluorouracil (5-FU) or 5-FU plus oxaliplatin (FOLFOX) is the standard therapy for colorectal cancer, it has met with limited success. Recurrence of the tumor after chemotherapy could partly be explained by the enrichment of the chemo-resistant sub-population of cancer stem cells (CSCs) that possess the ability for self-renewal and differentiation into different lineages in the tumor. Therefore… CONTINUE READING
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Publications referenced by this paper.
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Phenotypic characterization of human colorectal cancer stem cells.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 11 Excerpts
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Dasatinib in solid tumors.

Expert opinion on investigational drugs • 2010
View 2 Excerpts

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