Combination of cisplatin-procaine complex DPR with anticancer drugs increases cytotoxicity against ovarian cancer cell lines.

@article{Viale1998CombinationOC,
  title={Combination of cisplatin-procaine complex DPR with anticancer drugs increases cytotoxicity against ovarian cancer cell lines.},
  author={Maurizio Viale and Ilaria Pastrone and Claudio Pellecchia and Maria Ornella Vannozzi and Sergio Cafaggi and Mauro Esposito},
  journal={Anti-cancer drugs},
  year={1998},
  volume={9 5},
  pages={457-63}
}
DPR, cis-diamminechloro-[2-(diethylamino)ethyl 4-amino-benzoate, N4]-chlorideplatinum(II) monohydrochloride monohydrate, is a newly developed water-soluble platinum compound which possess minimal cross-resistance to cisplatin and shows relatively less side effects. In an attempt to establish whether the combination of DPR with other conventional anticancer… CONTINUE READING