Combination of bFGF, heparin and laminin induce the generation of dopaminergic neurons from rat neural stem cells both in vitro and in vivo.

@article{Yu2007CombinationOB,
  title={Combination of bFGF, heparin and laminin induce the generation of dopaminergic neurons from rat neural stem cells both in vitro and in vivo.},
  author={Yiqun Yu and Shuting Gu and Hai Huang and Tieqiao Wen},
  journal={Journal of the neurological sciences},
  year={2007},
  volume={255 1-2},
  pages={81-6}
}
Neural stem cells (NSCs) are self-renewing and pluripotent, which can differentiate into neurons, astrocytes and oligodendrocytes. Due to these properties, NSCs are supposed to be an ideal candidate to clinical purpose while research on cell replacement therapy to treat neural diseases has been widely investigated recently. In this article, we demonstrated a new and efficient method to induce the generation of proliferative dopaminergic neurons from rat NSCs in the presence of bFGF, heparin and… CONTINUE READING

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