Combination of Soy Protein, Amylopectin, and Chromium Stimulates Muscle Protein Synthesis by Regulation of Ubiquitin–Proteasome Proteolysis Pathway after Exercise

  title={Combination of Soy Protein, Amylopectin, and Chromium Stimulates Muscle Protein Synthesis by Regulation of Ubiquitin–Proteasome Proteolysis Pathway after Exercise},
  author={Veysi Kayri and Cemal Orhan and Mehmet Tuzcu and Patrick Brice Deeh Defo and Hafize Telceken and Mehmet Irmak and Nurhan Şahin and Hakkı Taştan and James Richard Komorowski and Kazım Şahin},
  journal={Biological Trace Element Research},
The present study was undertaken to investigate the effect of the combination of soy protein, amylopectin, and chromium (SAC) on muscle protein synthesis and signal transduction pathways involved in protein synthesis (mTOR pathways, IGF-1, and AktSer473) and proteolysis (FOXO1Ser256; MURF1, MAFbx) after exercise. Thirty-five Wistar rats were randomly divided into five groups: (1) control (C); (2) exercise (E); (3) exercise + soy protein (3.1 g/kg/day) (E + S); (4) exercise + soy protein… 



Post-exercise whey protein hydrolysate supplementation induces a greater increase in muscle protein synthesis than its constituent amino acid content

Results indicate that WPH may include active components that are superior to amino acids for stimulating muscle protein synthesis and initiating translation in skeletal muscle during the post-exercise phase.

Effects of an amylopectin and chromium complex on the anabolic response to a suboptimal dose of whey protein

These data indicate that the addition of ACr to a 6 g dose of whey protein (WPACr) increases the FSR response beyond what is seen with a suboptimal dose of Whey protein alone.

Feeding meals containing soy or whey protein after exercise stimulates protein synthesis and translation initiation in the skeletal muscle of male rats.

The data suggest that mTOR signaling in skeletal muscle is acutely responsive to physiological variations in dietary amino acids, and general protein synthesis and the mRNA cap binding step are promoted comparably by soy protein and whey protein in the skeletal muscle of exercised rats.

Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men.

It is concluded that the feeding-induced simulation of MPS in young men is greater after whey hydrolysate or soy protein consumption than casein both at rest and after resistance exercise; moreover, despite both being fast proteins, whey Hydrolysate stimulated MPS to a greater degree than soy after resistance Exercise.

Branched-chain amino acids activate key enzymes in protein synthesis after physical exercise.

The results suggest that B CAAs activate mTOR and p70 S6 kinase in human muscle in the recovery period after exercise and that GSK-3 is not involved in the anabolic action of BCAAs on human muscle.

Dietary protein and lactose increase translation initiation factor activation and tissue protein synthesis in neonatal pigs.

The results indicate that growth and protein synthesis rates in neonatal pigs are influenced by dietary protein and lactose intake and might be mediated by plasma amino acids and insulin levels, but feeding protein well above the piglet's requirement does not further stimulate the activation of translation initiation or protein synthesis in skeletal muscle and liver.

Effects of Whey, Caseinate, or Milk Protein Ingestion on Muscle Protein Synthesis after Exercise

It is concluded that ingestion of MP, CA or WP causes the initial peak time in muscle protein synthesis to occur at different times (WP, fast; MP, intermediate; CA, slow) and the dairy proteins have a superior effect on muscleprotein synthesis after exercise compared with SP.

Recent Perspectives Regarding the Role of Dietary Protein for the Promotion of Muscle Hypertrophy with Resistance Exercise Training

Recent advancements in the understanding of how protein ingestion impacts skeletal muscle growth following resistance exercise in young adults during energy balance and energy restriction are examined.

Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise.

Together, insulin and leucine allow skeletal muscle to coordinate protein synthesis with physiological state and dietary intake and are synergistic with insulin via the phosphoinositol 3-kinase signaling pathway.

Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice.

The results indicate that the ability of an overnight fast to decrease protein synthesis and the acute effects of insulin and IGF-I to stimulate protein synthesis are restricted to skeletal and cardiac muscles.