Combination of Bendroflumethiazide and Triamterene in the Treatment of Hypostatic Edema

@article{Haeger1969CombinationOB,
  title={Combination of Bendroflumethiazide and Triamterene in the Treatment of Hypostatic Edema},
  author={Knut Haeger},
  journal={Angiology},
  year={1969},
  volume={20},
  pages={334 - 340}
}
  • K. Haeger
  • Published 1 June 1969
  • Medicine
  • Angiology
* Associate Professor of Surgery, Vascular Section, Department of Surgery, Allmänna Sjukhuset, Malmö, Sweden. Diuretics as an adjunct in the treatment of acute and chronic hypostatic edema of the leg have been extensively studied in this clinic. 1-4 Contrary to the findings in cardiac patients, hypopotassemia does not constitute a problem in patients suffering from venous valvular incompetence. Among other factors, it is believed that the simultaneous administration of digitalis in heart… 

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Further Observations On the Effect of Diuretics On Stasis Edema of the Leg
TLDR
In 85 patients with edema due to venous insufficiency, and in 3 patients with lymphedema of the leg there was a remarkable reduction of body weight, a decrease of the circumference of the ankle and the calf and a reduction of leg volume, as measured by the water displacement method.
Clinical Experience with a New Diuretic, Triamterene, in Congestive Heart Failure
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Triamterene therapy was evaluated in 35 patients with congestive heart failure and its main therapeutic value is in the longterm management of chronic edema, especially in certain patients refractory to the currently used diuretics.
Triamterene, a New Diuretic Drug—II
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A review of the literature on Mechlanisms and Managrement from 1960 to 1961 by Edmonds, C. J and Wilson, G. M.
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