Combination is better than monotherapy with ACE inhibitor or angiotensin receptor antagonist at recommended doses.

@article{Segura2003CombinationIB,
  title={Combination is better than monotherapy with ACE inhibitor or angiotensin receptor antagonist at recommended doses.},
  author={J. M. Guiu Segura and Manuel Praga and Carlos Campo and Jos{\'e} Luis Rodicio and Luis M Ruilope},
  journal={Journal of the renin-angiotensin-aldosterone system : JRAAS},
  year={2003},
  volume={4 1},
  pages={43-7}
}
OBJECTIVE The combination of an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor antagonist (ARB) could provide a higher degree of blockade of the renin-angiotensin system(RAS) than either agent alone. The primary aim of this study was to look at the effect of three therapeutic regimens (titrated ACE inhibitor (ACE-I) versus titrated ARB versus the combination of an ACE-I and an ARB) on the attainment of adequate blood pressure (BP) control and… CONTINUE READING

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