Combination heparin plus cortisone treatment of two transplanted tumors in C3H/He mice.

@article{Penhaligon1985CombinationHP,
  title={Combination heparin plus cortisone treatment of two transplanted tumors in C3H/He mice.},
  author={Miranda Penhaligon and Richard S. Camplejohn},
  journal={Journal of the National Cancer Institute},
  year={1985},
  volume={74 4},
  pages={869-73}
}
C3H/He inbred mice bearing either C3H mouse mammary or RIF-1 tumors of 180-mm3 volume were treated with a combination of heparin (500 anticoagulation U/ml drinking water) plus cortisone (either 250 mg/kg/day tapering to 37 mg/kg/day or a constant dose of 75 mg/kg/day). Five types of heparin were tested in this study. RIF-1 tumors shrank to approximately half the volume at the start of therapy after only 3 days of treatment; mammary tumors took longer to respond, not reaching half the starting… CONTINUE READING

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