Combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in previously treated patients with advanced/recurrent head and neck cancer: a phase II feasibility study.

@article{Janinis2000CombinationCW,
  title={Combination chemotherapy with docetaxel, cisplatin, and 5-fluorouracil in previously treated patients with advanced/recurrent head and neck cancer: a phase II feasibility study.},
  author={Jim Janinis and M Papadakou and E Xidakis and H Boukis and Alexandros Poulis and G E Panagos and Dimitris Lefantzis},
  journal={American journal of clinical oncology},
  year={2000},
  volume={23 2},
  pages={128-31}
}
The purpose of this phase II feasibility trial was to determine the efficacy and toxicity of docetaxel combined with cisplatin and 5-fluorouracil in patients with locally advanced and/or recurrent squamous cell carcinoma of the head and neck. Nineteen patients entered the study. The majority had received prior radiotherapy but were chemotherapy naive. Treatment consisted of docetaxel 80 mg/m2 day 1, cisplatin 40 mg/m2 days 2 and 3, and 5-fluorouracil 1,000 mg/m2 by continuous infusion days 1 to… CONTINUE READING

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Current Treatment Options for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2015

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