Combination biological and surgical therapy in an adolescent presenting with highly destructive perianal Crohn disease.


784 Perianal CD (PCD) requiring treatment occurs in more than 40% of pediatric patients with CD (4,5). In adults, identifying PCD H ighly destructive perianal disease (HDPD) is a severe clinical manifestation of Crohn disease (CD) that is notoriously difficult to treat. It is diagnosed by visualization of deep perineal ulceration and tissue destruction… (More)
DOI: 10.1097/MPG.0b013e3181d32728


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