Combination antiretroviral therapy improves cognitive performance and functional connectivity in treatment-naïve HIV-infected individuals

@inproceedings{Zhuang2017CombinationAT,
  title={Combination antiretroviral therapy improves cognitive performance and functional connectivity in treatment-na{\"i}ve HIV-infected individuals},
  author={Yuchuan Zhuang and Xing Qiu and Lu Wang and Qing Ma and Mark Mapstone and Amneris Luque and Miriam Weber and Madalina E. Tivarus and Eric Miller and Roberto C. Arduino and Jianhui Zhong and Giovanni Schifitto},
  booktitle={Journal of NeuroVirology},
  year={2017}
}
Our study aimed to investigate the short-term effect of combination antiretroviral therapy (cART) on cognitive performance and functional and structural connectivity and their relationship to plasma levels of antiretroviral (ARV) drugs. Seventeen ARV treatment-naïve HIV-infected individuals (baseline mean CD4 cell count, 479 ± 48 cells/mm3) were age matched with 17 HIV-uninfected individuals. All subjects underwent a detailed neurocognitive and functional assessment and magnetic resonance… CONTINUE READING
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