Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia.

@article{Baddour2004CombinationAT,
  title={Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia.},
  author={Larry Baddour and Victor L. Yu and Keith P. Klugman and Charles Feldman and Ake Ortqvist and Jordi Rello and A. S. Morris and Carlos M Luna and David R. Snydman and Wen Chien Ko and Maria Bernadete Fernandes Chedid and David Shu-Cheong Hui and Antoine Andremont and C. C. Chiou},
  journal={American journal of respiratory and critical care medicine},
  year={2004},
  volume={170 4},
  pages={440-4}
}
Retrospective studies have suggested that combination antibiotic therapy for severe bacteremic pneumococcal pneumonia may reduce mortality. We assessed this issue in a prospective, multicenter, international observational study of 844 adult patients with bacteremia due to Streptococcus pneumoniae. The effect of combination antibiotic therapy versus monotherapy on mortality was examined by univariate analyses and by logistic regression models. The 14-day mortality was not significantly different… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 156 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 16 references

Bacteremic pneumococcal pneumonia in one 444 AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

  • MA Mufson, RJ Stanek
  • Am J Med
  • 2004
Highly Influential
5 Excerpts

standards for antimicrobial susceptibility testing: twelfth informational supplement

  • NCCLS. Performanc
  • Wayne, PA: National Committee for Clinical…
  • 2002
1 Excerpt

Similar Papers

Loading similar papers…