Combination adjuvant chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin after liver transplantation for hepatocellular carcinoma: a preliminary open-label study

@article{Zhang2011CombinationAC,
  title={Combination adjuvant chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin after liver transplantation for hepatocellular carcinoma: a preliminary open-label study},
  author={Qing Zhang and Hong Chen and Qin Li and Yunjin Zang and Xinguo Chen and Weilong Zou and Letian Wang and Zhong-yang Shen},
  journal={Investigational New Drugs},
  year={2011},
  volume={29},
  pages={1360-1369}
}
The purpose of this study was to evaluate the efficacy of postoperative adjuvant chemotherapy with FOLFOX regimen on the outcome after LT for HCC patients who did not meet the Milan criteria. Ninety-five consecutive HCC patients with liver cirrhosis undergoing LT were enrolled. Fifty-eight who did not meet the Milan criteria were randomized to open-label treatment with or without adjuvant chemotherapy after LT (n = 29/group). The FOLFOX chemotherapy protocol comprised 3-week cycles of… CONTINUE READING

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