Combination adjuvant chemotherapy for node-positive breast cancer. Inadequacy of a single perioperative cycle.

  • Published 1988 in The New England journal of medicine

Abstract

We studied the timing and duration of adjuvant chemotherapy for operable breast cancer with axillary-node involvement in a randomized trial including 1229 patients divided into three treatment groups. One group received a single perioperative course of adjuvant combination chemotherapy beginning within 36 hours of mastectomy; a second received six cycles of… (More)

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