Colposcopy: still useful in microbicide safety trials?

  title={Colposcopy: still useful in microbicide safety trials?},
  author={Christine K. Mauck and Debra H. Weiner and Jaim Jou Lai and Jill L. Schwartz},
  journal={Sexually transmitted diseases},
  volume={39 6},
BACKGROUND Colposcopy is used to evaluate vaginal microbicides, but its link to risk of HIV is unknown. This reanalysis of 9 safety studies determined the impact of omitting colposcopy on the number of findings detected and assessed whether colposcopy was useful in identifying nonoxynol-9 (N-9) as an unsafe product in one study. METHODS Product-related findings seen with naked eye and colposcopy or by colposcopy alone were evaluated. Using data from one study, the ratio of findings in N-9… CONTINUE READING
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