Colostrinin: an oxidative stress modulator for prevention and treatment of age-related disorders.

@article{Boldogh2008ColostrininAO,
  title={Colostrinin: an oxidative stress modulator for prevention and treatment of age-related disorders.},
  author={Istvan Boldogh and Marian L. Kruzel},
  journal={Journal of Alzheimer's disease : JAD},
  year={2008},
  volume={13 3},
  pages={303-21}
}
Colostrum-derived proline-rich polypeptide, also known as Colostrinin (CLN), has been shown to have a stabilizing effect on cognitive function in Alzheimer's disease patients. This complex action of CLN could be related to prevention of amyloid-beta peptide aggregation, as shown in in vitro studies, and its impact on delicate cassettes of signaling pathways common to cellular redox regulation, proliferation and differentiation. Studies on cultured cells showed that CLN modulates intracellular… CONTINUE READING