Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA.

@article{HonrioFrana2001ColostralNE,
  title={Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA.},
  author={Adenilda Cristina Hon{\'o}rio-França and Pierre Launay and Magda Maria Sales Carneiro-Sampaio and Renato C Monteiro},
  journal={Journal of leukocyte biology},
  year={2001},
  volume={69 2},
  pages={289-96}
}
Colostrum plays an important role in protecting newborn infants against acute gastrointestinal and respiratory infections. IgA antibodies have been considered the major effector component; however, the role of their receptors on colostral phagocytes, especially neutrophils, has not been studied. Here, we demonstrate that CD15+ colostrum neutrophils express IgA Fc receptors (Fc alphaR, CD89) at levels similar to those of blood neutrophils. Most colostral cells (70%) bear secretory IgA (SIgA) on… CONTINUE READING
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