Colorimetric detection of influenza A virus using antibody-functionalized gold nanoparticles.

@article{Liu2015ColorimetricDO,
  title={Colorimetric detection of influenza A virus using antibody-functionalized gold nanoparticles.},
  author={Yuanjian Liu and Linqun Zhang and Wei Wei and Hongyu Zhao and Zhenxian Zhou and Yuanjian Zhang and Songqin Liu},
  journal={The Analyst},
  year={2015},
  volume={140 12},
  pages={3989-95}
}
Early and accurate diagnosis is considered the key issue to prevent the further spread of viruses and facilitate influenza therapy. Herein, we report a colorimetric immunosensor for influenza A virus (IAV) based on gold nanoparticles (AuNPs) modified with monoclonal anti-hemagglutinin antibody (mAb). The immunosensor allows for a fast, simple, and selective detection of IAV. In this assay, influenza-specific antibodies are conjugated to AuNPs to create mAb-AuNP probes. Since IAV has multiple… CONTINUE READING
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