Colorimetric assay of matrix metalloproteinase activity based on metal-induced self-assembly of carboxy gold nanoparticles.

@article{Kim2013ColorimetricAO,
  title={Colorimetric assay of matrix metalloproteinase activity based on metal-induced self-assembly of carboxy gold nanoparticles.},
  author={Gae Baik Kim and Kun Hee Kim and Yeon Hee Park and Sungho Ko and Young-Pil Kim},
  journal={Biosensors & bioelectronics},
  year={2013},
  volume={41},
  pages={833-9}
}
Among proteases, matrix metalloproteinases (MMPs) have been of significant interest because they are considered as one of the promising biomarkers in association with cancer metastasis, inflammation and other degenerative diseases. Many attempts based on the optical sensing have been made to analyze the activity of MMPs, but most of them require an expensive fluorescence readout and a labor-intensive process. To circumvent this issue, we demonstrated a simple colorimetric detection of protease… CONTINUE READING