Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis

@inproceedings{Hirt2013ColorectalCI,
  title={Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis},
  author={Christian Hirt and Serenella Eppenberger-Castori and Giuseppe Sconocchia and Giandomenica Iezzi and Luigi Tornillo and Luigi Terracciano and Giulio Cesare Spagnoli and Raoul A. Droeser},
  booktitle={Oncoimmunology},
  year={2013}
}
The prognostic relevance of innate immune cells infiltrating colorectal carcinoma lesions is highly debated. By evaluating the expression of myeloperoxidase (MPO) as a marker of neutrophil granulocytes in a large cohort of colorectal carcinoma specimens, we have observed that robust tumor-infiltration by MPO+ cells correlates with improved patient survival independently of other histopathological parameters, including disease stage. 

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