Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism

Abstract

Colorectal cancer develops in a multi-step manner from normal epithelium, through a pre-malignant lesion (so-called adenoma), into a malignant lesion (carcinoma), which invades surrounding tissues and eventually can spread systemically (metastasis). It is estimated that only about 5% of adenomas do progress to a carcinoma. The present study aimed to unravel… (More)
DOI: 10.1007/s13402-011-0065-1

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@inproceedings{Carvalho2011ColorectalAT, title={Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism}, author={Beatriz Freias de Carvalho and Anke H. Sillars-Hardebol and Cindy Postma and Sandra Mongera and Jochim S. Terhaar sive Droste and Askar Obulkasim and Mark A. van de Wiel and Wim van Criekinge and Bauke Ylstra and Remond J. A. Fijneman and Gerrit Meijer}, booktitle={Cellular Oncology}, year={2011} }