Colorectal Carcinogenesis: Role of Oxidative Stress and Antioxidants.

  title={Colorectal Carcinogenesis: Role of Oxidative Stress and Antioxidants.},
  author={Francesco Carini and Margherita Mazzola and Francesca Rappa and Abdo R. Jurjus and Alice Gerges Geagea and Sahar Al Kattar and Tarek Bou-Assi and Rosalyn A. Jurjus and Provvidenza Damiani and Angelo Leone and Giovanni Tomasello},
  journal={Anticancer research},
  volume={37 9},
One of the contributory causes of colon cancer is the negative effect of reactive oxygen species on DNA repair mechanisms. Currently, there is a growing support for the concept that oxidative stress may be an important etiological factor for carcinogenesis. The purpose of this review is to elucidate the role of oxidative stress in promoting colorectal carcinogenesis and to highlight the potential protective role of antioxidants. Several studies have documented the importance of antioxidants in… CONTINUE READING
3 Citations
46 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 46 references

Targeted therapies for IBD and CRC: An increasing need for microbiotaintestinal mutualism

  • G Tomasello, P Tralongo, A Jurjus, MatarM, L Angelo
  • J Int Transl Med
  • 2015
Highly Influential
3 Excerpts

Inflammatory bowel disease and colorectal cancer, nutraceutical aspects

  • M Mazzola, F Carini, +8 authors G Tomasello
  • EMBJ
  • 2016

Research progress on antioxidant activity of natural products

  • L Chen, X Zhang, +4 authors S Tang
  • European Journal of BioMedical Research
  • 2016

Evaluation of oxidative stress and its impact on the antioxidant activities in patients with colorectal carcinoma

  • SK Singh, AK Nigam, D Maraiya, N Singh
  • Int J Sci Res
  • 2015

Intestinal microbiota mutualism and gastrointestinal diseases

  • A Leone, G Tomasello, +7 authors R Jurjus
  • EMBJ
  • 2015

Similar Papers

Loading similar papers…