Colorectal Carcinogenesis: Role of Oxidative Stress and Antioxidants.

@article{Carini2017ColorectalCR,
  title={Colorectal Carcinogenesis: Role of Oxidative Stress and Antioxidants.},
  author={Francesco Carini and Margherita Mazzola and Francesca Rappa and Abdo R. Jurjus and Alice Gerges Geagea and Sahar Al Kattar and Tarek Bou-Assi and Rosalyn A. Jurjus and Provvidenza Damiani and Angelo Leone and Giovanni Tomasello},
  journal={Anticancer research},
  year={2017},
  volume={37 9},
  pages={4759-4766}
}
One of the contributory causes of colon cancer is the negative effect of reactive oxygen species on DNA repair mechanisms. Currently, there is a growing support for the concept that oxidative stress may be an important etiological factor for carcinogenesis. The purpose of this review is to elucidate the role of oxidative stress in promoting colorectal carcinogenesis and to highlight the potential protective role of antioxidants. Several studies have documented the importance of antioxidants in… CONTINUE READING
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