Colony stimulating factors for prevention of myelosupressive therapy induced febrile neutropenia in children with acute lymphoblastic leukaemia.

@article{Sasse2005ColonySF,
  title={Colony stimulating factors for prevention of myelosupressive therapy induced febrile neutropenia in children with acute lymphoblastic leukaemia.},
  author={Emma Chen Sasse and Andre Deeke Sasse and S{\'i}lvia Regina Brandalise and Ot{\'a}vio Augusto Camara Clark and Sue Richards},
  journal={The Cochrane database of systematic reviews},
  year={2005},
  volume={3},
  pages={CD004139}
}
BACKGROUND Acute lymphoblastic leukaemia (ALL) is the most common cancer in childhood and febrile neutropenia is a potentially life-threatening side effect of its treatment. Current treatment consists of supportive care plus antibiotics. Clinical trials have attempted to evaluate the use of colony-stimulating factors (CSF) as additional therapy to prevent febrile neutropenia in children with ALL. The individual trials do not show whether there is significant benefit or not. Systematic review… CONTINUE READING
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