Colony growth and self renewal of plasma cell precursors in multiple myeloma.

@article{Takahashi1985ColonyGA,
  title={Colony growth and self renewal of plasma cell precursors in multiple myeloma.},
  author={Toshiyuki Takahashi and Bing Lim and Nazir Jamal and David Tritchler and Gina A. Lockwood and Steven McKinney and Daniel E. Bergsagel and Hans A. Messner},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1985},
  volume={3 12},
  pages={1613-23}
}
Culture conditions that support the growth of multi-and single-lineage hemopoietic colonies are also able to give rise to large myeloma colonies from bone marrow and peripheral blood samples of some patients with multiple myeloma. The culture system was used to determine the frequency of hemopoietic precursors and clonogenic myeloma progenitors in 71 patients with multiple myeloma studied in various clinical phases of the disease. The frequency of normal hemopoietic precursors in patients with… CONTINUE READING

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