Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.

@article{D1971ColonizationRO,
  title={Colonization resistance of the digestive tract in conventional and antibiotic-treated mice.},
  author={van der Waaij D and J M Berghuis-de Vries and Lekkerkerk Lekkerkerk-v},
  journal={The Journal of hygiene},
  year={1971},
  volume={69 3},
  pages={405-11}
}
The effect of oral administration of antibiotics on the intestinal flora of conventional mice and their resistance to colonization by orally introduced Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa was studied. Colonization resistance (CR) was expressed as the log of the oral bacterial dose followed by a persistent take in 50% of the contaminated animals. The intestinal flora was virtually eliminated by the antibiotics and this elimination was accompanied by a precipitous… CONTINUE READING
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Eliminating bacteria from monkeys with antibiotics

  • WAAIJ, D. VAN DER, VRIES, DE J.M., J.E.C. LEKEESKEBK
  • In Infections and Immunosuppression in Subhuman…
  • 1970

Similarities between GF mice and mice with an antibiotic decontaminated digestive tract

  • WAAIJ, D. VAN DER
  • In Germfree Biology,
  • 1969

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