Colonic perineuriomas with and without crypt serration: a comparative study.


Colorectal perineuriomas are characterized by a mucosal proliferation of benign stromal cells expressing perineurial markers leading to separation and/or disorganization of the crypts that frequently display a serrated/hyperplastic architecture. Previous studies demonstrated a high prevalence of a BRAF p.V600E mutation in perineuriomas with serrated crypts… (More)
DOI: 10.1097/PAS.0b013e318277a1a9