Colonic mucin synthesis is increased by sodium butyrate.

@article{Finnie1995ColonicMS,
  title={Colonic mucin synthesis is increased by sodium butyrate.},
  author={I. A. Finnie and Anandapuram D. Dwarakanath and Ben A. Taylor and JonathanM. Rhodes},
  journal={Gut},
  year={1995},
  volume={36 1},
  pages={
          93-9
        }
}
The effects of sodium butyrate and sodium bromo-octanoate (an inhibitor of beta oxidation) on colonic mucus glycoprotein (mucin) synthesis have been assessed using tissue from colonic resection samples. Epithelial biopsy specimens were incubated for 16 hours in RPMI 1640 with glutamine, supplemented with 10% fetal calf serum and N-acetyl-[3H]-glucosamine ([3H]-Glc NAc), and differing concentrations of sodium butyrate. Incorporation of [3H] Glc NAc into mucin by normal epithelium at least 10 cm… CONTINUE READING

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  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
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