Colonic microbiome is altered in alcoholism.

  title={Colonic microbiome is altered in alcoholism.},
  author={Ece A. Mutlu and P. M. Gillevet and Huzefa Rangwala and Masoumeh Sikaroodi and Ammar Naqvi and Phillip A Engen and Mary Morrissey Kwasny and Cynthia Lau and Ali Keshavarzian},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={302 9},
Several studies indicate the importance of colonic microbiota in metabolic and inflammatory disorders and importance of diet on microbiota composition. The effects of alcohol, one of the prominent components of diet, on colonic bacterial composition is largely unknown. Mounting evidence suggests that gut-derived bacterial endotoxins are cofactors for alcohol-induced tissue injury and organ failure like alcoholic liver disease (ALD) that only occur in a subset of alcoholics. We hypothesized that… CONTINUE READING
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