Colonic Migrating Motor Complexes, High Amplitude Propagating Contractions, Neural Reflexes and the Importance of Neuronal and Mucosal Serotonin

@inproceedings{Smith2014ColonicMM,
  title={Colonic Migrating Motor Complexes, High Amplitude Propagating Contractions, Neural Reflexes and the Importance of Neuronal and Mucosal Serotonin},
  author={Terence Keith Smith and Kyu Joo Park and Grant W. Hennig},
  booktitle={Journal of neurogastroenterology and motility},
  year={2014}
}
The colonic migrating motor complex (CMMC) is a critical neurally mediated rhythmic propulsive contraction observed in the large intestine of many mammals. It seems to be equivalent to the high amplitude propagating contractions (HAPCs) in humans. This review focuses on the probable neural mechanisms involved in producing the CMMC or HAPC, their likely de-pendence on mucosal and neuronal serotonin and pacemaker insterstitial cells of Cajal networks and how intrinsic neural re-flexes affect them… CONTINUE READING

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