Colon targeted drug delivery systems: a review on primary and novel approaches.

@article{Philip2010ColonTD,
  title={Colon targeted drug delivery systems: a review on primary and novel approaches.},
  author={Anil Kumar Philip and Betty Philip},
  journal={Oman medical journal},
  year={2010},
  volume={25 2},
  pages={79-87}
}
The colon is a site where both local and systemic delivery of drugs can take place. Local delivery allows topical treatment of inflammatory bowel disease. However, treatment can be made effective if the drugs can be targeted directly into the colon, thereby reducing the systemic side effects. This review, mainly compares the primary approaches for CDDS (Colon Specific Drug Delivery) namely prodrugs, pH and time dependent systems, and microbially triggered systems, which achieved limited success… CONTINUE READING
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