Colocalization of centromeric and replicative functions on autonomously replicating sequences isolated from the yeast Yarrowia lipolytica.

@article{Fournier1993ColocalizationOC,
  title={Colocalization of centromeric and replicative functions on autonomously replicating sequences isolated from the yeast Yarrowia lipolytica.},
  author={Pierrick G. J. Fournier and Abdelhamid Abbas and Marion Chasles and Bernard Kudla and David M. Ogrydziak and Debbie S. Yaver and James J W Xuan and A Peito and Andr{\'e} Ribet and C. Feynerol},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 11},
  pages={4912-6}
}
Two sequences (ARS18 and ARS68) displaying autonomous replication activity were previously cloned in the yeast Yarrowia lipolytica. The smallest fragment (1-1.3 kb) required for extrachromosomal replication of a plasmid is significantly larger in Y. lipolytica than in Saccharomyces cerevisiae. Neither autonomously replicating sequence (ARS) is homologous with known ARS or centromere (CEN) consensus sequences. They share short regions of sequence similarity with each other. These ARS fragments… CONTINUE READING

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