Colocalization of acidic and basic fibroblast growth factor (FGF) in human placenta and the cellular effects of bFGF in trophoblast cell line JEG-3.

@article{Ferriani1994ColocalizationOA,
  title={Colocalization of acidic and basic fibroblast growth factor (FGF) in human placenta and the cellular effects of bFGF in trophoblast cell line JEG-3.},
  author={Rui Alberto Ferriani and Asif Ahmed and Andrew S. Sharkey and Sally K. Sommers Smith},
  journal={Growth factors},
  year={1994},
  volume={10 4},
  pages={
          259-68
        }
}
The placenta undergoes extensive angiogenesis and cellular proliferation to establish adequate blood supply to the fetus. The aim of this study was to compare and contrast the immunolocalization of acidic and basic fibroblast growth factor (FGF) in both first trimester and term placenta and gestational decidua. Human choriocarcinoma cell line JEG-3 were employed as a model of cytotrophoblast and the effect of basic FGF on cell proliferation and phospholipase C and D activation investigated… CONTINUE READING
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