Colocalization of H(+)-ATPase and band 3 anion exchanger in rabbit collecting duct intercalated cells.

@article{Schuster1991ColocalizationOH,
  title={Colocalization of H(+)-ATPase and band 3 anion exchanger in rabbit collecting duct intercalated cells.},
  author={Victor L. Schuster and G{\'e}za Fejes-T{\'o}th and Anik{\'o} N{\'a}ray-Fejes-T{\'o}th and Stephen Gluck},
  journal={The American journal of physiology},
  year={1991},
  volume={260 4 Pt 2},
  pages={F506-17}
}
Two major types of intercalated cells (IC) have been previously defined in rabbit collecting duct: alpha-cells have a basolateral band 3-like anion exchanger and secrete H+, whereas beta-cells bind peanut agglutinin (PNA) apically and are believed to secrete HCO3-. To further define IC types, we double-labeled kidney sections with anti-H(+) -ATPase antibodies and with either an anti-band 3 antibody or PNA. We found four patterns of staining: 1) IC with apical H(+)-ATPase and basal band 3, a… CONTINUE READING