Colloquium: Physical approaches to DNA sequencing and detection
@article{Zwolak2008ColloquiumPA, title={Colloquium: Physical approaches to DNA sequencing and detection}, author={M. Zwolak and M. Ventra}, journal={Reviews of Modern Physics}, year={2008}, volume={80}, pages={141-165} }
With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and rapid interrogation of individual genomes. This capability is likely to be provided by a physical approach to probing DNA at the single-nucleotide level. This is in sharp contrast to current techniques and instruments that probe (through chemical… CONTINUE READING
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