Colloquium: Physical approaches to DNA sequencing and detection

  title={Colloquium: Physical approaches to DNA sequencing and detection},
  author={M. Zwolak and M. Ventra},
  journal={Reviews of Modern Physics},
  • M. Zwolak, M. Ventra
  • Published 2008
  • Physics, Biology
  • Reviews of Modern Physics
  • With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and rapid interrogation of individual genomes. This capability is likely to be provided by a physical approach to probing DNA at the single-nucleotide level. This is in sharp contrast to current techniques and instruments that probe (through chemical… CONTINUE READING
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