• DOI:10.1103/RevModPhys.80.141
Corpus ID: 1928204

Colloquium: Physical approaches to DNA sequencing and detection

@article{Zwolak2008ColloquiumPA,
  title={Colloquium: Physical approaches to DNA sequencing and detection},
  author={M. Zwolak and M. Ventra},
  journal={Reviews of Modern Physics},
  year={2008},
  volume={80},
  pages={141-165}
}

M. Zwolak, M. Ventra

Published 2008

Physics, Biology

Reviews of Modern Physics

With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, a revolutionary sequencing method is needed for the cost-effective and rapid interrogation of individual genomes. This capability is likely to be provided by a physical approach to probing DNA at the single-nucleotide level. This is in sharp contrast to current techniques and instruments that probe (through chemical… CONTINUE READING

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