Colloidal aggregation and the in vitro activity of traditional Chinese medicines.

Abstract

Traditional Chinese Medicines (TCMs) have been the sole source of therapeutics in China for two millennia. In recent drug discovery efforts, purified components of TCM formulations have shown activity in many in vitro assays, raising concerns of promiscuity. Here, we investigated 14 bioactive small molecules isolated from TCMs for colloidal aggregation. At… (More)
DOI: 10.1021/cb5009487

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