Colloidal Dispersions (Liposomes and Ethosomes) for Skin Drug Delivery and their Role on Rheumatoid Arthritis

  title={Colloidal Dispersions (Liposomes and Ethosomes) for Skin Drug Delivery and their Role on Rheumatoid Arthritis},
  author={Madhavi Nimmathota},
  journal={Asian Journal of Pharmaceutics},
Aim: The aim of the present work was to focus on the applicability of liposomes and ethosomes for transdermal delivery. In the current review, we had focused on transdermal delivery transdermal delivery of vesicular system vesicular systems, i.e., liposome and ethosomes, factors affecting their permeation and penetration efficiency, limitations, applications, method of preparations, evaluation parameters, and selection of lipids. In this review, we considered the mechanism of controlled drug… Expand
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Tapentadol is an anti-inflammatory drug and mostly used rheumatoid arthritis commonly at 200mg an oral dose twice daily. Because of its first-pass metabolism, its bioavailability is low (32%).ToExpand
Design by optimization and comparative evaluation of vesicular gels of etodolac for transdermal delivery
The vesicular gels of etodolac loaded liposomes and ethosomes for effective transdermal delivery showed desirable results compared to other test formulations. Expand
Ethosomal systems are lipid vesicular carriers which containing high percentage of ethanol. These nanocarriers are formulated to overcome the limitations associated with conventional oral therapy.Expand
Polymer Coating of an Optimized Nano Lipid Carrier System of Harpagophytum Procumbens Extract for Oral Delivery
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Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes.
Evaluated transdermal potential of novel vesicular carrier, ethosomes, bearing methotrexate (MTX), an anti-psoriatic, anti-neoplastic, highly hydrosoluble agent, suggests that ethosomes are an efficient carrier for dermal andtransdermal delivery of MTX. Expand
Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib
Among the various vesicular formulations examined in the study, Tween 20-ethosomes can be considered the most promising one as carrier for topical celecoxib applications aimed to prevent skin cancer development and increase the anticancer drugs effectiveness against skin tumors. Expand
Formulation, characterization and ex vivo studies of terbinafine HCl liposomes for cutaneous delivery.
The prolonged retention of drug by the gum karaya gel loaded with liposomal dispersion could effectively exhibit the antifungal activity for prolonged periods for cutaneous delivery. Expand
Enhanced Transdermal Delivery of Diclofenac Sodium via Conventional Liposomes, Ethosomes, and Transfersomes
Results revealed that both ethosome and transfersome formulations can act as drug reservoir in skin and extend the pharmacologic effects of Diclofenac sodium. Expand
Ethosomal nanocarriers: the impact of constituents and formulation techniques on ethosomal properties, in vivo studies, and clinical trials
A detailed review on the effects of ethosomal system constituents, preparation methods, and their significant roles in determining the final properties of these nanocarriers is given. Expand
Formulation Development and in vitro Characterization of Proliposomes for Topical Delivery of Aceclofenac
Development and characterized a vesicular drug carrier system (proliposome) for topical delivery of aceclofenac to overcome the problems related with oral route and stability study was performed at various temperatures indicating that acecl ofenac proliposomes are stable at lower temperature. Expand
Melatonin loaded ethanolic liposomes: physicochemical characterization and enhanced transdermal delivery.
  • Vaibhav Dubey, Dinesh Mishra, N. K. Jain
  • Chemistry, Medicine
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2007
A better skin tolerability of ethosomal suspension on rabbit skin suggested that ethosomes may offer a suitable approach for transdermal delivery of melatonin. Expand
Liposomes and parameters affecting their skin penetration behaviour
It is known that classical and more recently deformable liposomes have shown their ability to increase dermal and transdermal drug delivery. However their penetration mechanism remains controversialExpand
Carriers in the topical treatment of skin disease.
Topical drug application is less prone to severe systemic side-effects than systemic application, and a breakthrough appears likely, once stability problems (nanoparticles) and safety concerns (dendrimers) are overcome. Expand
Phycocyanin liposomes for topical anti-inflammatory activity: in-vitro in-vivo studies.
The results showed that C-PC can be successfully used as an anti- inflammatory drug and that liposomal encapsulation is effective in improving its anti-inflammatory activity. Expand