• Corpus ID: 239049405

Collective gradient sensing with limited positional information

  title={Collective gradient sensing with limited positional information},
  author={Emiliano Perez Ipi{\~n}a and Brian A. Camley},
Eukaryotic cells sense chemical gradients to decide where and when to move. Clusters of cells can sense gradients more accurately than individual cells by integrating measurements of the concentration made across the cluster. Is this gradient sensing accuracy impeded when cells have limited knowledge of their position within the cluster, i.e. limited positional information? We apply maximum likelihood estimation to study gradient sensing accuracy of a cluster of cells with finite positional… 

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  • Brian A. Camley
  • Computer Science, Medicine
    Journal of physics. Condensed matter : an Institute of Physics journal
  • 2018
Experimental evidence showing that cells collectively sense gradients of many signal types, and the models and physical principles involved are discussed, and new routes by which experiments and theory can expand the understanding of these problems are proposed.