• Corpus ID: 220665716

Collective Motility, Mechanical Waves, and Durotaxis in Cell Clusters

@article{Deng2020CollectiveMM,
  title={Collective Motility, Mechanical Waves, and Durotaxis in Cell Clusters},
  author={Youyuan Deng and Herbert Levine and Xiaoming Mao and Leonard M. Sander},
  journal={arXiv: Biological Physics},
  year={2020}
}
When epithelial cell clusters move in a collective manner on a substrate mechanical signals play a major role in organizing the coherent behavior. There are a number of unexplained experimental results from traction force microscopy for a system of this type (MDCK cell clusters). These include: the internal strains are tensile even for clusters that expand by proliferation; the tractions on the substrate are confined to the edges of the cluster; in many cases there are density waves within the… 
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