Collection of biological samples in forensic toxicology

@article{DinisOliveira2010CollectionOB,
  title={Collection of biological samples in forensic toxicology},
  author={R. Dinis-Oliveira and F. Carvalho and J. Duarte and F. Remi{\~a}o and A. Marques and A. Santos and T. Magalh{\~a}es},
  journal={Toxicology Mechanisms and Methods},
  year={2010},
  volume={20},
  pages={363 - 414}
}
Forensic toxicology is the study and practice of the application of toxicology to the purposes of the law. The relevance of any finding is determined, in the first instance, by the nature and integrity of the specimen(s) submitted for analysis. This means that there are several specific challenges to select and collect specimens for ante-mortem and post-mortem toxicology investigation. Post-mortem specimens may be numerous and can endow some special difficulties compared to clinical specimens… Expand
Review on Collection , Preservation and Fowarding of Biological Samples for Toxicological Analysis
TLDR
An overview is given on sampling procedures for routinely collected specimens as well as on alternative specimens that may provide additional information on the route and timing of exposure to a specific xenobiotic. Expand
Analytical Methods of Compounds in Biological Specimens: Applications in Forensic Toxicology
Toxicology is defined as the study of adverse effects of drugs, chemicals and any other xenobiotics on biological systems. Forensic toxicology is the application of toxicology cases and issues whereExpand
State of the art in bile analysis in forensic toxicology.
TLDR
An update on the state of knowledge for the use of bile in forensic toxicology is provided, through a review of the Medline literature from 1970 to May 2015, to highlight specificities and consequences from an analytical and interpretative point of view. Expand
Guidelines for Collection of Biological Samples for Clinical and Forensic Toxicological Analysis
TLDR
General procedures for sampling of routinely collected as well as on alternative samples that may provide additional information regarding intoxication are reviewed. Expand
1.23 – Legal and Forensic Sampling
This chapter covers the diverse topics within sampling and sample preparation for forensic chemical analysis. Sampling and sample preparation are the first and sometimes neglected steps in obtainingExpand
Cerebrospinal fluid in forensic toxicology: Current status and future perspectives.
TLDR
It is very difficult to assess the possibility of using CSF as an alternative biological material for toxicological studies for the presence of drugs, intoxicants, including new psychoactive substances (commonly known as designer drugs), psychotropic substances, and ethyl alcohol, based on current data. Expand
Postmortem Toxicology: Artifacts
TLDR
This article attempts to highlight the most important known artifacts with regard to the antemortem setting and changes of the corpse, and hence the matrices and drugs therein. Expand
Interés de las muestras para los estudios químico-toxicológicos post mortem
TLDR
Issues associated with the selection and the usefulness of samples when postmortem toxicological studies are required are reviewed. Expand
Chapter 8 – Analytical Samples
TLDR
This chapter provides an overview of the characteristics, handling, advantages, and disadvantages of various analytical samples including blood, urine, breath, vitreous humor, hair, oral fluid, nails, sweat, gastric contents, liver, bile, brain, lung, adipose tissues, bone and bone marrow, skeletal muscle, breast milk, neonatal samples, and nonhuman samples. Expand
Putrified tissue analysis: A challenge for Forensic toxicologists
TLDR
The aim of present study is to describe the type of biological samples submitted for toxicological analysis in forensic toxicology section and factors associated with their analysis. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 509 REFERENCES
Requirements for bioanalytical procedures in postmortem toxicology
  • O. Drummer
  • Chemistry, Medicine
  • Analytical and bioanalytical chemistry
  • 2007
The application of analytical techniques in postmortem toxicology is often more difficult than in other forms of forensic toxicology owing to the variable and often degraded nature of the specimensExpand
Preanalytic aspects in postmortem toxicology.
  • G. Skopp
  • Medicine
  • Forensic science international
  • 2004
TLDR
An overview is given on specimens routinely collected as well as on alternative specimens that may provide additional information on the route of administration, a long term or a recent use/exposure to a drug or poison. Expand
Value of hair analysis in postmortem toxicology.
  • P. Kintz
  • Medicine
  • Forensic science international
  • 2004
TLDR
The aim of this review is to document the current status of hair analysis in postmortem toxicology. Expand
Interpretation of Analytical Toxicology Results in Life and at Postmortem
TLDR
Information is presented to assist in the interpretation of analytical results, especially regarding postmortem toxicology, which is an especially complex area since changes in the composition of fluids such as blood depending on the site of collection from the body and the time elapsed since death, amongst other factors, may influence the result obtained. Expand
Postmortem forensic toxicology.
TLDR
The cause of death is determined and items such as route of administration, acute versus chronic dose, and consistency between drug concentrations and behavioral effects may be critical factors in assessing the manner of death. Expand
The role of alternative specimens in toxicological analysis.
TLDR
This paper reviews a series of publications on the use of alternative specimens, with special focus on the main analytical and chromatographic problems that these samples present, as well on their advantages and disadvantages over traditional samples in documenting drug exposure. Expand
Postmortem toxicology of drugs of abuse.
  • O. Drummer
  • Medicine
  • Forensic science international
  • 2004
TLDR
Toxicological issues associated with the more common drugs of abuse such as the amphetamines, cannabinoids, cocaine, opioids and the benzodiazepines are reviewed. Expand
Postmortem Drug Analysis: Analytical and Toxicological Aspects
TLDR
Publications focusing on the analysis of postmortem specimens for the presence of drugs were reviewed with particular reference to systematic toxicological analysis, finding few practical differences in the assays validated for a range of post autopsy specimens to those in other forms of forensic toxicology. Expand
Evaluation of an onsite alcohol testing device for use in postmortem forensic toxicology.
TLDR
Although the QED saliva alcohol test does not appear to be useful in determining postmortem saliva ethanol levels, it does provide accurate results when using postmortem vitreous humor as the testing matrix. Expand
Stability of analytes in biosamples—an important issue in clinical and forensic toxicology?
  • F. Peters
  • Medicine
  • Analytical and bioanalytical chemistry
  • 2007
TLDR
The data presented show that the majority of drugs are stable in blood, plasma, or serum samples under the conditions usually encountered in a clinical or forensic toxicology laboratory. Expand
...
1
2
3
4
5
...