Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion.

Abstract

NH3 movement across plasma membranes has traditionally been ascribed to passive, lipid-phase diffusion. However, ammonia-specific transporters, Mep/Amt proteins, are present in primitive organisms and mammals express orthologs of Mep/Amt proteins, the Rh glycoproteins. These findings suggest that the mechanisms of NH3 movement in mammalian tissues should be… (More)
DOI: 10.1152/ajprenal.90667.2008

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@article{Lee2009CollectingDR, title={Collecting duct-specific Rh C glycoprotein deletion alters basal and acidosis-stimulated renal ammonia excretion.}, author={Hyunwook Lee and Jill W Verlander and Jesse Bishop and Peter Igarashi and Mary E. Handlogten and I David Weiner}, journal={American journal of physiology. Renal physiology}, year={2009}, volume={296 6}, pages={F1364-75} }