Collagens of basement membranes.

  title={Collagens of basement membranes.},
  author={H L Sage},
  journal={The Journal of investigative dermatology},
  volume={79 Suppl 1},
  • H L Sage
  • Published 1982 in The Journal of investigative dermatology
Recent biochemical and immunohistochemical studies have described several components of basement membranes including heparan sulfate proteoglycan, 2 high molecular weight glycoproteins (fibronectin and laminin), and 2 collagen types (IV and V). These collagens have several properties which distinguish them from other types that are located in the interstitium: (a) type IV forms an amorphous, felt-like matrix, and neither IV nor V is found in large, cross-banded fibrils, (b) both have an… CONTINUE READING
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