Collagenase inhibition by water-pepper (Polygonum hydropiper L.) sprout extract

@article{Kawaguchi2019CollagenaseIB,
  title={Collagenase inhibition by water-pepper (Polygonum hydropiper L.) sprout extract},
  author={T. Kawaguchi and Kaori Nagata},
  journal={Journal of HerbMed Pharmacology},
  year={2019},
  volume={8},
  pages={114-119}
}
Introduction: Collagenase plays an important role in the degradation of dermal matrix proteins leading to wrinkle formation. The objectives of this study were to evaluate the inhibitory effect of water-pepper (Polygonum hydropiper L.) sprout extract on the activity of collagenase and to identify the inhibitory compounds.Methods: Collagenase inhibitory activity was measured by spectrophotometric assay. Activity-guided fractionation was performed using liquid-liquid extraction of water and n… Expand
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