Collagen type IV-specific tripeptides for selective adhesion of endothelial and smooth muscle cells.

@article{Kanie2012CollagenTI,
  title={Collagen type IV-specific tripeptides for selective adhesion of endothelial and smooth muscle cells.},
  author={Kei Kanie and Yuji Narita and Yingzi Zhao and Fumiaki Kuwabara and Makoto Satake and Susumu Honda and Hiroaki Kaneko and Tomohiko Yoshioka and Mina Okochi and Hiroyuki Honda and Ryuji Kato},
  journal={Biotechnology and bioengineering},
  year={2012},
  volume={109 7},
  pages={1808-16}
}
Controlling the balance of endothelial cells (ECs) and smooth muscle cells (SMCs) in blood vessels is critically important to minimize the risk associated with vascular implants. Extracellular matrix (ECM) plays a key role in controlling the cellular balance, suggesting a promising source of cell-selective peptides. To obtain EC- or SMC-selective peptides, we start by highlighting sequence differences found among ECM molecules as enriched targets for cell-selective peptides. We explored the EC… CONTINUE READING
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