Collagen type I hydrogel allows migration, proliferation, and osteogenic differentiation of rat bone marrow stromal cells.

@article{Hesse2010CollagenTI,
  title={Collagen type I hydrogel allows migration, proliferation, and osteogenic differentiation of rat bone marrow stromal cells.},
  author={Eric Hesse and Theresa E. Hefferan and James Tarara and Carl Haasper and Rupert Meller and Christian Krettek and Lichun Lu and Michael J. Yaszemski},
  journal={Journal of biomedical materials research. Part A},
  year={2010},
  volume={94 2},
  pages={442-9}
}
Hydrogels are potentially useful for many purposes in regenerative medicine including drug and growth factor delivery, as single scaffold for bone repair or as a filler of pores of another biomaterial in which host mesenchymal progenitor cells can migrate in and differentiate into matrix-producing osteoblasts. Collagen type I is of special interest as it is a very important and abundant natural matrix component. The purpose of this study was to investigate whether rat bone marrow stromal cells… CONTINUE READING