Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study.

@article{Kharaishvili2011CollagenTH,
  title={Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study.},
  author={Gvantsa Kharaishvili and Magdalena Cizkova and Kateřina Bouchalov{\'a} and Giorgi Mgebrishvili and Zdeněk Kol{\'a}ř and Jan Bouchal},
  journal={Journal of clinical pathology},
  year={2011},
  volume={64 11},
  pages={
          977-82
        }
}
BACKGROUND Collagen triple helix repeat containing 1 (CTHRC1) affects Wnt signalling, collagen deposition and bone formation. It is an extracellular matrix protein which is also abnormally expressed in the tumour microenvironment. CTHRC1 has not been studied in breast cancer by immunohistochemistry. AIMS To examine expression of CTHRC1 together with periostin and versican in breast cancer patients and investigate its association with clinicopathological characteristics. METHODS The formalin… CONTINUE READING
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