Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes.

  title={Collagen-phosphorylcholine interpenetrating network hydrogels as corneal substitutes.},
  author={Wenguang Liu and Chao Deng and Christopher R McLaughlin and Per Fagerholm and Neil S Lagali and Belinda J M Heyne and Juan C Scaiano and Mitchell A. Watsky and Yasuhiro Kato and Rejean M Munger and Naoshi Shinozaki and Fengfu Li and May Griffith},
  volume={30 8},
A biointeractive collagen-phospholipid corneal substitute was fabricated from interpenetrating polymeric networks comprising 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide and N-hydroxysuccinimide crosslinked porcine atelocollagen, and poly(ethylene glycol) diacrylate crosslinked 2-methacryloyloxyethyl phosphorylcholine (MPC). The resulting hydrogels showed an overall increase in mechanical strength beyond that of either original component and enhanced stability against enzymatic digestion (by… CONTINUE READING