Collagen-like complement component C1q is a membrane protein of human monocyte-derived macrophages that mediates endocytosis.

@article{Kaul1995CollagenlikeCC,
  title={Collagen-like complement component C1q is a membrane protein of human monocyte-derived macrophages that mediates endocytosis.},
  author={Marcus Kaul and M. R. de Loos},
  journal={Journal of immunology},
  year={1995},
  volume={155 12},
  pages={5795-802}
}
The collagen-like C1q molecule, a subcomponent of the first component of complement, C1, is synthesized by macrophages (M phi). Previously, we have demonstrated that C1q is a membrane protein of guinea pig peritoneal macrophages (M phi). To extend this observation as a general biologic characteristic of M phi, we investigated human (hu) monocyte-derived M phi. Interestingly, surface labeling with the biotin derivative sulfosuccinimidyl-6-(biotinamido)-hexanoate of M phi, freshly isolated… CONTINUE READING
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