Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta.

@article{Borges2008CollagenIR,
  title={Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta.},
  author={Luciano de Figueiredo Borges and Rodrigo Gibin Jaldin and Ricardo Ribeiro Dias and Noedir Ant{\^o}nio Groppo Stolf and Jean-Baptiste Michel and Paulo Sampaio Gutierrez},
  journal={Human pathology},
  year={2008},
  volume={39 3},
  pages={437-43}
}
In ascending aorta aneurysms, there is an enlargement of the whole vessel, whereas aortic dissections (ADs) are characterized by the cleavage of the wall into 2 sheets at the external half. We searched if alterations in collagen could be related to these diseases. Sections of aortas from 14 case patients with acute dissections, 10 case patients with aneurysms, and 9 control subjects were stained with picrosirius. Slides were analyzed under polarized microscopy to evaluate the structure of… CONTINUE READING

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