Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders:a review of the literature

@article{Bello2006CollagenHF,
  title={Collagen hydrolysate for the treatment of osteoarthritis and other joint disorders:a review of the literature},
  author={Alfonso E. Bello and Steffen Oesser},
  journal={Current Medical Research and Opinion},
  year={2006},
  volume={22},
  pages={2221 - 2232}
}
  • A. Bello, S. Oesser
  • Published 10 October 2006
  • Medicine
  • Current Medical Research and Opinion
BACKGROUND There is a need for an effective treatment for the millions of people in the United States with osteoarthritis (OA), a degenerative joint disease. [] Key Method Articles were obtained through searches of the PubMed database (www.pubmed.gov) through May 2006 using several pairs of key words (collagen hydrolysate and osteoarthritis; collagen hydrolysate and cartilage; collagen hydrolysate and chondrocytes; collagen hydrolysate and clinical trial) without date limits.
POTENCY OF ORAL UN-DENATURED TYPE II COLLAGENIN THE TREATMENT OF OSTEOARTHRITIS, WITH SPECIFICAL RELATIONSHIP TO KNEE JOINT- A META-ANALYTIC REVIEW
TLDR
Type II Undenatured Collagen, is a relatively safe and also signicantly more efcient, in improving the joint function, ROM and for the alleviation of bone joint pain, in OA knee (Genu OA) patients.
A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?
TLDR
This White Paper aims to stimulate research and development of collagen-based supplements for patients with OA and other musculoskeletal diseases at academic and industrial levels and highlight opportunities for scientific innovation and interdisciplinary collaboration.
The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery from joint injury and exercise: a systematic review
TLDR
The results indicated that COL is most beneficial in improving joint functionality and reducing joint pain, and certain improvements in body composition, strength and muscle recovery were present.
Therapeutic Activity of Collagen and Rosehip Extracts: A Review
TLDR
Options for therapeutic activity of hydrolysate are explored for the treatment of osteoarthritis and other joint disorders and as a dietary supplement in athletes with activity-related joint pain.
[An overview of the beneficial effects of hydrolysed collagen intake on joint and bone health and on skin ageing].
TLDR
Clinical studies show that HC continual ingestion helps to reduce and prevent joint pain, bone density loss and skin ageing, and its high level of tolerance and safety make HC ingestion attractive for a long-term use in bone and joint degenerative diseases and in fight against skin ageing.
Collagen Metabolism of Human Osteoarthritic Articular Cartilage as Modulated by Bovine Collagen Hydrolysates
TLDR
It is found that various collagen hydrolysates obtained from different sources varied with respect to the width of molecular weight distribution, average molecular weight, and aggregation behavior, as well as by their pharmacological efficacy on human chondrocytes.
Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: a randomized, double-blind, placebo-controlled trial.
TLDR
BCC was well tolerated and found to be effective in managing OA-associated symptoms over the study period, thereby improving patient's activities of daily living and can be considered a potential complement to current OA therapies.
ect of the Novel Low Molecular Weight Hydrolyzed Chicken Sternal Cartilage Extract , BioCell Collagen , on Improving Osteoarthritis-Related Symptoms : A Randomized , Double-Blind , Placebo-Controlled Trial
TLDR
BCC was well tolerated and found to be effective in managing OA-associated symptoms over the study period, thereby improving patient’s activities of daily living and can be considered a potential complement to current OA therapies.
Impact of collagen hydrolysate in middle-aged athletes with knee and ankle osteochondral lesions: A case series
TLDR
MRI images of patients assessed in this study depict the recovery of the articular surfaces after the treatment of OCL, and studies in athletes presenting joint pain but otherwise not diagnosed with osteoarthritis or other osteoarticular diseases have demonstrated the beneficial effects of CH intake.
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TLDR
Collagen hydrolysate is of interest as a therapeutic agent of potential utility in the treatment of osteoarthritis and osteoporosis, and its high level of safety makes it attractive as an agent for long-term use in these chronic disorders.
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