Collagen gel immobilisation provides a suitable cell matrix for long term human hepatocyte cultures in hybrid reactors.

Abstract

An easy to apply culture technique is presented that protects a monolayer configuration of liver cells within an extracellular matrix. The Immobilising Gel (IG)-Technique not only preserves hepatocyte morphology and supports a variety of differentiated cell functions over long term periods, but also offers higher resistance of IG-culture systems against… (More)

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