Collagen fibrils: nanoscale ropes.

@article{Bozec2007CollagenFN,
  title={Collagen fibrils: nanoscale ropes.},
  author={Laurent Bozec and G. H. M. van der Heijden and Michael Horton},
  journal={Biophysical journal},
  year={2007},
  volume={92 1},
  pages={70-5}
}
The formation of collagen fibrils from staggered repeats of individual molecules has become "accepted" wisdom. However, for over thirty years now, such a model has failed to resolve several structural and functional questions. In a novel approach, it was found, using atomic force microscopy, that tendon collagen fibrils are composed of subcomponents in a spiral disposition-that is, their structure is similar to that of macroscale ropes. Consequently, this arrangement was modeled and confirmed… CONTINUE READING

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